This Practice Brief was developed as result of the roundtable dialogue that occurred at the 2019 PBIS Leadership Forum in Chicago, IL and provides an overview of the process of designing and implementing Tier 2 systems and practices within a Positive Behavioral Interventions & Supports (PBIS) framework. Approaching Tier 2 design from the district-level is encouraged; however, considerations and suggestions for schools implementing Tier 2 independent of a district-level initiative are included.